Shougang Zhuang Selected Research

Extracellular Matrix Proteins

1/2022	Targeting lysine-specific demethylase 1A inhibits renal epithelial-mesenchymal transition and attenuates renal fibrosis.
10/2016	Pharmacological targeting of BET proteins inhibits renal fibroblast activation and alleviates renal fibrosis.
1/2014	Recent advances in renal interstitial fibrosis and tubular atrophy after kidney transplantation.
7/2013	Sustained activation of EGFR triggers renal fibrogenesis after acute kidney injury.
6/2011	Suramin inhibits renal fibrosis in chronic kidney disease.
8/2010	A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy.

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Shougang Zhuang Research Topics

Disease

57	Fibrosis (Cirrhosis) 01/2022 - 07/2008
26	Acute Kidney Injury (Acute Renal Failure) 01/2022 - 06/2005
22	Inflammation (Inflammations) 01/2022 - 03/2010
19	Chronic Renal Insufficiency 01/2021 - 08/2010
18	Ureteral Obstruction 12/2020 - 10/2009
14	Neoplasms (Cancer) 10/2022 - 11/2010
13	Kidney Diseases (Kidney Disease) 01/2022 - 08/2010
11	Peritoneal Fibrosis 10/2022 - 11/2014
9	Ischemia 01/2022 - 12/2006
7	Sepsis (Septicemia) 07/2021 - 04/2013
6	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 04/2016
6	Reperfusion Injury 01/2019 - 02/2009
5	Chronic Kidney Failure (Chronic Renal Failure) 12/2021 - 09/2015
5	Peritonitis 12/2021 - 12/2011
5	Lung Injury 07/2021 - 05/2017
5	Hyperuricemia 01/2021 - 11/2015
4	Hypoxia (Hypoxemia) 01/2022 - 03/2014
4	Insulin Resistance 07/2021 - 01/2017
4	Necrosis 05/2021 - 06/2008
4	Sclerosis 05/2017 - 01/2012
3	Lupus Nephritis 01/2022 - 01/2015
3	Rhabdomyolysis 01/2021 - 08/2014
3	Hyperglycemia 01/2020 - 08/2015
3	Pathologic Processes 01/2020 - 07/2015
3	Wounds and Injuries (Trauma) 01/2020 - 12/2006
3	Hypertension (High Blood Pressure) 01/2020 - 04/2013
3	Myocardial Infarction 01/2019 - 10/2014
3	Proteinuria 01/2016 - 06/2011
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2016 - 06/2008
2	IGA Glomerulonephritis (IGA Nephropathy) 12/2021 - 04/2016
2	Pulmonary Fibrosis (Fibrosing Alveolitis) 07/2021 - 10/2016
2	Hyperinsulinism (Hyperinsulinemia) 01/2020 - 01/2017
2	Idiopathic Pulmonary Fibrosis 01/2019 - 08/2017
2	Myocardial Ischemia (Ischemic Heart Diseases) 01/2018 - 04/2012

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2013
11	Histone Deacetylases (Histone Deacetylase)IBA 01/2021 - 10/2009
10	CytokinesIBA 05/2021 - 06/2011
10	ErbB Receptors (EGF Receptor)IBA 01/2020 - 07/2003
9	Cisplatin (Platino)FDA LinkGeneric 01/2022 - 12/2006
9	CollagenIBA 05/2021 - 07/2008
8	Histones (Histone)IBA 01/2022 - 01/2016
8	Lysine (L-Lysine)FDA Link 01/2022 - 01/2016
8	Fibronectins (Fibronectin)IBA 01/2022 - 06/2011
8	Histone Deacetylase InhibitorsIBA 12/2020 - 10/2009
7	chlorhexidine gluconate (Dyna-Hex)FDA LinkGeneric 10/2022 - 11/2014
7	Enhancer of Zeste Homolog 2 ProteinIBA 10/2022 - 01/2016
7	MethyltransferasesIBA 01/2022 - 01/2016
7	Suramin (Suramin Sodium)IBA 11/2019 - 02/2009
6	3-deazaneplanocinIBA 10/2022 - 05/2018
6	Extracellular Matrix ProteinsIBA 01/2022 - 08/2010
6	Therapeutic UsesIBA 01/2022 - 11/2010
6	Histone MethyltransferasesIBA 07/2021 - 05/2018
6	Uric Acid (Urate)IBA 01/2020 - 11/2015
5	Histone Deacetylase 6IBA 12/2021 - 01/2017
5	Glucose (Dextrose)FDA LinkGeneric 07/2021 - 01/2016
5	ChemokinesIBA 05/2021 - 11/2015
5	Phosphotransferases (Kinase)IBA 01/2019 - 06/2008
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2022 - 01/2020
4	Cadherins (E-Cadherin)IBA 01/2022 - 05/2018
4	Interleukin-6 (Interleukin 6)IBA 05/2021 - 01/2017
4	Pharmaceutical PreparationsIBA 01/2021 - 01/2012
4	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2019 - 06/2011
4	Caspase 3 (Caspase-3)IBA 01/2019 - 08/2014
4	src-Family KinasesIBA 01/2019 - 01/2017
4	HSP72 Heat-Shock ProteinsIBA 04/2016 - 07/2008
3	Arginine (L-Arginine)FDA Link 01/2022 - 01/2020
3	Dialysis SolutionsIBA 01/2022 - 10/2017
3	nintedanibIBA 05/2021 - 08/2017
3	Biomarkers (Surrogate Marker)IBA 11/2020 - 01/2019
3	Collagen Type I (Type I Collagen)IBA 01/2020 - 06/2011
3	Protein Isoforms (Isoforms)IBA 01/2020 - 01/2018
3	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2019 - 09/2015
3	Folic Acid (Vitamin M)FDA LinkGeneric 08/2017 - 02/2013
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2014 - 06/2011
3	Epidermal Growth Factor (EGF)IBA 05/2013 - 06/2005
2	Polycomb Repressive Complex 2IBA 10/2022 - 01/2022
2	Small Interfering RNA (siRNA)IBA 10/2022 - 08/2014
2	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2022 - 01/2020
2	Insulin (Novolin)FDA Link 07/2021 - 01/2020
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 05/2021 - 01/2017
2	IronIBA 01/2021 - 01/2019
2	Circular RNAIBA 01/2021 - 10/2019
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 10/2016
2	GSK1210151AIBA 01/2021 - 10/2016
2	LipopolysaccharidesIBA 12/2020 - 12/2011
2	Matrix Metalloproteinases (MMPs)IBA 03/2019 - 01/2019
2	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2019 - 08/2017
2	Lipocalin-2IBA 01/2019 - 08/2014
2	Xanthine OxidaseIBA 01/2019 - 01/2019
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2019 - 08/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018 - 03/2010
2	tubastatin AIBA 01/2018 - 01/2017

Therapy/Procedure

12	Peritoneal Dialysis 10/2022 - 12/2011
8	Therapeutics 01/2021 - 12/2011
4	Ligation 01/2021 - 10/2014
3	Nephrectomy 01/2022 - 01/2012
3	Renal Dialysis (Hemodialysis) 01/2020 - 07/2013
3	Intraperitoneal Injections 10/2017 - 11/2014
2	Kidney Transplantation 01/2021 - 01/2014
2	Renal Replacement Therapy (Therapies, Renal Replacement) 12/2020 - 11/2020